Research status of serum amyloid A in infection: a bibliometric analysis

Ann Palliat Med. 2022 Jun;11(6):2007-2016. doi: 10.21037/apm-22-487.

Abstract

Background: Infectious diseases have a significant impact on health. Identifying the pathogenic kind of an infection has important implications for the clinical selection of therapy. Serum amyloid A has been found to have significant changes in expression levels upon infection. The purpose of the present study was to analyze the current status of research on the use of serum amyloid A in infection using a bibliometric approach.

Methods: The Science Citation Index Expanded database in the Web of Science Core Collection (WOSCC) was used as the data source for our search. All search records and cited references were exported in plain text format to form source files for further analysis. Cytoscape software was then used to analyze the source files and generate corresponding visualization graphs.

Results: A total of 1,359 relevant research papers were searched, with a total of 56,607 citations. Core journals included PLoS One, Frontiers in Immunology, and Developmental and Comparative Immunology. The main research countries in this field were the USA, UK, and Denmark. The most cited scholars included JJ Ceron from Spain and MB Pepys from the UK.

Conclusions: There is a limited number of studies on serum amyloid A in infection. More international cooperation and in-depth research are needed.

Keywords: Serum amyloid A; bibliometrics; infection.

MeSH terms

  • Bibliometrics*
  • Humans
  • Serum Amyloid A Protein*
  • Spain

Substances

  • Serum Amyloid A Protein