Renal metastasis of osteosarcoma after multiple pulmonary metastases: A case report and review of literature

Reuben Yih Khai Ooi; Syaza Ab Rahman; Yen Fa Toh; Ahmad Nazran Fadzli; Teng Aik Ong

doi:10.1016/j.eucr.2022.102174

Renal metastasis of osteosarcoma after multiple pulmonary metastases: A case report and review of literature

Urol Case Rep. 2022 Jul 31:45:102174. doi: 10.1016/j.eucr.2022.102174. eCollection 2022 Nov.

Authors

Reuben Yih Khai Ooi¹, Syaza Ab Rahman², Yen Fa Toh³, Ahmad Nazran Fadzli¹, Teng Aik Ong¹

Affiliations

¹ Department of Urology, University of Malaya Medical Centre, 59100, Kuala Lumpur, Malaysia.
² Department of Paediatrics, University of Malaya Medical Centre, 59100, Kuala Lumpur, Malaysia.
³ Department of Pathology, University of Malaya Medical Centre, 59100, Kuala Lumpur, Malaysia.

Abstract

Renal metastasis of osteosarcoma is a rare entity, with paucity of reported cases in the literature. We report a case of a 20-year-old gentleman who was diagnosed with right distal femur osteosarcoma, complicated with multiple pulmonary recurrences. At two-year-and-a-half interval post-treatment completion, the patient developed right flank pain and frank haematuria. Contrasted abdominal computed tomography revealed a right renal mass with calcification and perinephric haematoma. A right radical nephrectomy was undertaken and histopathological examination showed metastatic condroblastic osteosarcoma. A literature review on renal metastasis secondary to osteosarcoma was performed and we present a report and discussion of these cases.

Keywords: Nephrectomy; Osteosarcoma; Relapse; Renal metastasis.

Publication types

Case Reports