Chemical constituents and their pharmacological activities of plants from Cichorium genus

Haji Akber Aisa; Xue-Lei Xin; Dan Tang

doi:10.1016/j.chmed.2020.05.001

Chemical constituents and their pharmacological activities of plants from Cichorium genus

Chin Herb Med. 2020 May 15;12(3):224-236. doi: 10.1016/j.chmed.2020.05.001. eCollection 2020 Jul.

Authors

Haji Akber Aisa^{1

2}, Xue-Lei Xin^{1

2}, Dan Tang^{1

2}

Affiliations

¹ Key Laboratory of Plant Resources and Chemistry of Arid Zone, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi 830011, China.
² State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi 830011, China.

Abstract

Plants of genus Cichorium are famous due to their therapeutic and medicinal properties. They are used as traditional medicine and edible food. To date, several scholars concentrated on compounds belonging to coumarins, flavonoids, sesquiterpenoids, triterpenoids, steroids, organic acids and other chemical constituents. Pharmacological effects such as photo-protective, hepatoprotective, anti-diabetic and lipid lowering, antioxidant, anti-inflammation, antifungal, antimalarial, increased bone mineral density, as well as vasorelaxant and antitumour activity were wildly reported. In this study, botanical resources, ethnopharmacological application, chemical constituents and bioactivities, as well as safety and toxicity of clinical applications of genus Cichorium were reviewed, which may provide a reliable basis for further development and utilization of Cichorium genetic resources.

Keywords: Cichorium endivia L.; Cichorium intybus L.; Cichorum glandulosum Boiss. et Huet; chemical constituents; ethanopharmacological application; pharmacological activities.

Publication types

Review