Starving cancer into submission by activating BAT

Cell Metab. 2022 Oct 4;34(10):1428-1430. doi: 10.1016/j.cmet.2022.09.009.

Abstract

Activated brown adipose tissue (BAT) consumes copious amounts of circulating nutrients to fuel thermogenesis. Recently writing in Nature, Seki et al. show that this property can be leveraged to limit glucose availability for cancer cells and slow tumor growth, thereby adding cancer to the growing list of diseases that can potentially be treated by activating BAT.

Publication types

  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Adipose Tissue, Brown* / metabolism
  • Energy Metabolism
  • Glucose / metabolism
  • Humans
  • Neoplasms* / metabolism
  • Thermogenesis

Substances

  • Glucose