A pilot study of same-day MRI-only simulation and treatment with MR-guided adaptive palliative radiotherapy (MAP-RT)

Clin Transl Radiat Oncol. 2022 Dec 15:39:100561. doi: 10.1016/j.ctro.2022.100561. eCollection 2023 Mar.

Abstract

We conducted a prospective pilot study evaluating the feasibility of same day MRI-only simulation and treatment with MRI-guided adaptive palliative radiotherapy (MAP-RT) for urgent palliative indications (NCT#03824366). All (16/16) patients were able to complete 99% of their first on-table attempted fractions, and no grades 3-5 toxicities occurred.

Keywords: Adaptive radiation; CT Simulation-Free; Electron density calculations; MRI; Palliative radiation; Physics; Treatment.