High-resolution mass spectrometry for glycoproteomics

Bioanalysis. 2023 Jan;15(2):57-61. doi: 10.4155/bio-2023-0027. Epub 2023 Mar 9.

Abstract

Tweetable abstract Bottom-up glycoproteomics combined with top-down strategy allows direct analysis of glycoform-mapped glycosylation and its glycans by high-resolution mass spectrometry.

Keywords: HRMS; glycopeptide; glycoprotein; high-resolution mass spectrometry; top-down.

MeSH terms

  • Glycopeptides / analysis
  • Glycoproteins* / analysis
  • Glycosylation
  • Mass Spectrometry / methods
  • Polysaccharides* / analysis

Substances

  • Glycoproteins
  • Polysaccharides
  • Glycopeptides