Worldwide productivity and research trend of publications concerning electroactive materials and spinal cord injury: A bibliometric study

Sirui Liu; Lin Song; Weishu Dai; Mengdie Liu; Huijing Zhang; Xueyan Zhang; Hongyu Li; Xiu Liu; Yan Lv; Ying Hu

doi:10.3389/fbioe.2023.1094059

Worldwide productivity and research trend of publications concerning electroactive materials and spinal cord injury: A bibliometric study

Front Bioeng Biotechnol. 2023 Feb 27:11:1094059. doi: 10.3389/fbioe.2023.1094059. eCollection 2023.

Authors

Sirui Liu¹, Lin Song^{1

2}, Weishu Dai¹, Mengdie Liu^{3

4}, Huijing Zhang^{1

2}, Xueyan Zhang¹, Hongyu Li¹, Xiu Liu¹, Yan Lv¹, Ying Hu¹

Affiliations

¹ Beijing Institute of Dental Research, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
² Department of Periodontology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
³ The Third Medical Center of PLA General Hospital, Beijing, China.
⁴ The First Medical Center of PLA General Hospital, Beijing, China.

Abstract

Purpose: We investigated the current state and trends in the area during the previous 10 years using bibliometric approaches to evaluate the global scientific output of research on electroactive materials and spinal cord injury. Methods: Studies on spinal cord injury in electroactive materials that were published between 2012 and 2022 were located using the Web of science (WOS) datebase. The software programs bibliometrix R-package and CiteSpace were used to do quantitative analyses of annual publications, nation, author, institution, journal source, co-cited references, and keywords. The studies were categorized by the research's main points using a qualitative analysis, and publications having more than 10 citations each year. Results: In the final analysis, 1,330 relevant papers or reviews were included. There is an increased tendency in both the average annual citation rate and the number of publications in the discipline. The United States and the University of Toronto are the countries and institutions that have contributed the most to this discipline, respectively. The majority of authors are from the China and United States. Zhang Y is the author with the most published articles and holds the top position in the cited author h-index species. The journal with the highest number of published articles is "Disability and rehabilitation"; the journal is divided into four main areas including physics, materials, chemistry, molecular, and biology. The keyword analysis revealed a shift in research hotspots from schwann cell, fracture, and urinary disorders to carbon-based materials, functional recovery, and surgery. Analysis of qualitative data revealed that the role and mechanism of injectable conductive hydrogels in spinal cord healing after damage is a hot topic of current study, with the mechanism primarily focusing on the inhibition of oxidative stress (Nrf2) and apoptosis (Casepase 3). Conclusion: Our bibliometric analysis indicates that research on electroactive materials for spinal cord injury remains an active field of study. Moreover, contemporary research is concentrated on carbon-based materials, functional rehabilitation, and surgery.

Keywords: Citespace; bibliometrix; biomaterials; electroactive materials; spinal cord injury.

Grants and funding

This study was Supported by Beijing Natural Science Foundation (7214236), General Project of Scientific Research Program of Beijing Municipal Education commission (KM202110025010), Beijing Hospitals Authority Innovation Studio of Young Staff Funding Support (202133), Beijing Municipal Science Technology Commission (Z211100002921066) and Innovation Research Team Project of Beijing Stomatological Hospital, Capital Medical University (CXTD202204).