Case Report: Tumor-to-tumor metastasis with prostate cancer metastatic to lung cancer: the first reported case

Front Oncol. 2023 Aug 18:13:1238331. doi: 10.3389/fonc.2023.1238331. eCollection 2023.

Abstract

Tumor-to-tumor metastasis (TTM) occurs rarely in tumor progression, but this event has significant clinical implications. Although the impact of TTM on patient prognosis and survival has been increasingly recognized, understanding of TTM biology and treatment is limited. Prostate cancer is among the most common malignancies threatening male health. Prostate cancer can potentially metastasize to primary lung Cancer; however, this is an exceedingly rare event. We here report for the first time a case of TTM from a prostate cancer to a coexisting primary lung cancer.

Keywords: adenocarcinoma; lung cancer; metastases; prostate cancer; tumor-to-tumor metastasis.

Publication types

  • Case Reports

Grants and funding

This study was supported by National Natural Science Foundation of China (Grants number: 82200214), Key Research and Development Project of Hubei (Grants number: 2022BCE028), Young and middle-aged talent program of Hubei Education Bureau (Grants number: Q20222101), Platform Special Fund for Scientific Research of Xiangyang No.1 People’s Hospital (Grants number: XYY2022P05) and Instructional projects of Hubei Provincial Health and Health Commission (WJ2023F074). This work was supported by the Foundation of Hubei Xiangyang No. 1 People’s Hospital of Youth programs (XYYY2021Q07) and Hubei Natural Science Foundation (No, B2018106).