Cytoskeleton crosstalk: Casting stable actin bundles with dynamic microtubule molds

Farah Haque; Radhika Subramanian

doi:10.1016/j.cub.2023.12.028

Cytoskeleton crosstalk: Casting stable actin bundles with dynamic microtubule molds

Curr Biol. 2024 Jan 22;34(2):R72-R74. doi: 10.1016/j.cub.2023.12.028.

Authors

Farah Haque¹, Radhika Subramanian²

Affiliations

¹ Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
² Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA. Electronic address: radhika@molbio.mgh.harvard.edu.

PMID: 38262365
DOI: 10.1016/j.cub.2023.12.028

Abstract

Actin-microtubule crosstalk diversifies cytoskeletal networks. A new study provides insight into how the microtubule polymerase CKAP5 mediates actin-microtubule crosstalk. CKAP5 directs the assembly of stable actin bundles on dynamic microtubules; in turn, the actin bundles align growing microtubules along their length.

Publication types

Comment

MeSH terms

Actins*
Cytoskeleton*
Fungi
Microtubules
Nucleotidyltransferases

Substances

Actins
Nucleotidyltransferases