Novel CMY-186 variant conferring cross-resistance to cefiderocol and ceftazidime/avibactam in Klebsiella pneumoniae from a critically ill patient during cefiderocol and ceftazidime/avibactam treatment

Int J Antimicrob Agents. 2024 Apr;63(4):107107. doi: 10.1016/j.ijantimicag.2024.107107. Epub 2024 Feb 6.
No abstract available

Publication types

  • Letter

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Anti-Bacterial Agents / therapeutic use
  • Azabicyclo Compounds / pharmacology
  • Azabicyclo Compounds / therapeutic use
  • Bacterial Proteins
  • Cefiderocol
  • Ceftazidime* / pharmacology
  • Ceftazidime* / therapeutic use
  • Critical Illness
  • Drug Combinations
  • Humans
  • Klebsiella Infections* / drug therapy
  • Klebsiella pneumoniae / genetics
  • Microbial Sensitivity Tests
  • beta-Lactamases

Substances

  • Ceftazidime
  • Cefiderocol
  • avibactam
  • Anti-Bacterial Agents
  • Azabicyclo Compounds
  • Drug Combinations
  • beta-Lactamases
  • Bacterial Proteins