Medical management of obesity

Clin Med (Lond). 2023 Jul;23(4):323-329. doi: 10.7861/clinmed.2023-0183.

Abstract

Obesity is a global epidemic that has worsened over the past few decades. It is strongly associated with multiple health conditions, including type 2 diabetes mellitus, cardiovascular diseases, obstructive sleep apnoea, certain malignancies and has an increased mortality risk. The annual cost of obesity to the NHS is around £6 billion, projected to increase to just under £10 billion by 2050. In 2020-2021, obesity was cited as a factor in over 1 million hospital admissions. An early and pragmatic approach to the management of obesity would reduce obesity-associated multiple health conditions and result in cost savings for the NHS. Here, we discuss current management strategies for obesity, including dietary intervention, pharmacological therapies and optimisation, and bariatric surgery.

Keywords: GLP-1 agonist; Obesity; bariatric surgery; weight; weight management.

MeSH terms

  • Bariatric Surgery*
  • Cross-Sectional Studies
  • Diabetes Mellitus, Type 2* / complications
  • Diabetes Mellitus, Type 2* / epidemiology
  • Diabetes Mellitus, Type 2* / therapy
  • Humans
  • Multimorbidity
  • Obesity / complications
  • Obesity / epidemiology
  • Obesity / therapy