Treatment of essential hypertension with a new vasodilator in combination with beta-adrenergic blockade

N Engl J Med. 1970 Mar 5;282(10):521-7. doi: 10.1056/NEJM197003052821001.
No abstract available

MeSH terms

  • Adrenergic alpha-Antagonists / therapeutic use
  • Adult
  • Aldosterone / urine
  • Antihypertensive Agents / administration & dosage*
  • Antihypertensive Agents / pharmacology
  • Blood Pressure / drug effects
  • Cardiac Output / drug effects
  • Female
  • Forearm / blood supply
  • Glomerular Filtration Rate
  • Heart / drug effects
  • Heart Rate / drug effects
  • Humans
  • Hypertension / drug therapy*
  • Kidney / blood supply
  • Male
  • Middle Aged
  • Norepinephrine / urine
  • Piperidines / therapeutic use
  • Posture
  • Propranolol / pharmacology
  • Propranolol / therapeutic use*
  • Pyrimidines / therapeutic use*
  • Sodium / metabolism
  • Valsalva Maneuver
  • Vanilmandelic Acid / urine
  • Vascular Resistance / drug effects
  • Vasodilator Agents / therapeutic use*

Substances

  • Adrenergic alpha-Antagonists
  • Antihypertensive Agents
  • Piperidines
  • Pyrimidines
  • Vasodilator Agents
  • Aldosterone
  • Vanilmandelic Acid
  • Sodium
  • Propranolol
  • Norepinephrine