Controlled trial of penfluridol in acute psychosis

Br Med J. 1971 Dec 18;4(5789):710-3. doi: 10.1136/bmj.4.5789.710.

Abstract

A controlled study was made of penfluridol medication consisting of a single weekly oral dose of 30 mg in 30 patients with acute psychoses of varying type and origin. This medication was found to be effective. No significant side effects occurred.Several long-acting neuroleptics for injection are now available. The development of an oral compound of this type is an asset because of the manageability of the oral drug in the hands of family doctors and social psychiatrists.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Acute Disease
  • Administration, Oral
  • Adult
  • Aged
  • Chlorpromazine / therapeutic use
  • Clinical Trials as Topic
  • Delusions / drug therapy
  • Female
  • Hallucinations / drug therapy
  • Humans
  • Hydrocarbons, Halogenated / administration & dosage
  • Hydrocarbons, Halogenated / therapeutic use
  • Male
  • Middle Aged
  • Paranoid Disorders / drug therapy
  • Piperidines / administration & dosage
  • Piperidines / therapeutic use*
  • Psychomotor Disorders / drug therapy
  • Psychotic Disorders / drug therapy*
  • Time Factors
  • Tranquilizing Agents / administration & dosage
  • Tranquilizing Agents / therapeutic use*

Substances

  • Hydrocarbons, Halogenated
  • Piperidines
  • Tranquilizing Agents
  • Chlorpromazine