Abstract
Of 10 distinct cloned DNA copies of mRNAs expressed in T lymphocytes but not in B lymphocytes and associated with membrane-bound polysomes, one hybridizes to a region of the genome that has rearranged in a T-cell lymphoma and several T-cell hybridomas. These characteristics suggest that it encodes one chain of the elusive antigen receptor on the surface of T lymphocytes.
MeSH terms
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Animals
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B-Lymphocytes / immunology
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Cell Membrane / immunology
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Cloning, Molecular*
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DNA / isolation & purification*
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Genes
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Liver / immunology
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Mice
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Mice, Inbred Strains
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Nucleic Acid Hybridization
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Poly A / genetics
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Polyribosomes / metabolism
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RNA / genetics
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RNA, Messenger / genetics
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Receptors, Antigen, T-Cell / genetics*
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T-Lymphocytes / immunology*
Substances
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RNA, Messenger
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Receptors, Antigen, T-Cell
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Poly A
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RNA
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DNA