Diabetic ketoacidosis

Pediatr Clin North Am. 1984 Jun;31(3):591-610. doi: 10.1016/s0031-3955(16)34608-9.

Abstract

In the past decade, considerable advances have occurred in our understanding of the pathophysiology of this disorder, its metabolic sequelae, and its management, particularly with respect to continuous low-dose insulin infusion and the potential benefits of phosphate. This article reviews these advances as they pertain to children.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Bicarbonates / therapeutic use
  • Brain Edema / etiology
  • Child
  • Child, Preschool
  • Diabetic Ketoacidosis / complications
  • Diabetic Ketoacidosis / physiopathology*
  • Diabetic Ketoacidosis / therapy
  • Epinephrine / metabolism
  • Fluid Therapy
  • Glucagon / metabolism
  • Growth Hormone / metabolism
  • Humans
  • Hydrocortisone / metabolism
  • Insulin / metabolism
  • Insulin / therapeutic use
  • Insulin Secretion
  • Ketone Bodies / metabolism
  • Phosphates / therapeutic use
  • Water-Electrolyte Balance

Substances

  • Bicarbonates
  • Insulin
  • Ketone Bodies
  • Phosphates
  • Growth Hormone
  • Glucagon
  • Hydrocortisone
  • Epinephrine