Efficacy of topical anaesthetics

Ophthalmic Res. 1984;16(3):135-8. doi: 10.1159/000265308.

Abstract

By means of a recently developed electronical optical esthesiometer the efficacy of five different topical anaesthetics was compared. The influence of vehicle and concentration was also investigated. From the results it can be concluded that the drugs currently available are of suitable local anaesthetic effect with little influence of the vehicle or preservative agent used.

Publication types

  • Comparative Study

MeSH terms

  • Anesthetics, Local / pharmacology*
  • Anesthetics, Local / standards
  • Cornea / drug effects*
  • Cornea / physiology
  • Dose-Response Relationship, Drug
  • Drug Evaluation
  • Electronics, Medical / instrumentation
  • Humans
  • Ophthalmic Solutions
  • Procaine / administration & dosage
  • Procaine / analogs & derivatives*
  • Procaine / pharmacology
  • Sensation / drug effects

Substances

  • Anesthetics, Local
  • Ophthalmic Solutions
  • Procaine
  • benoxinate