Constituents of Agaricus xanthodermus Genevier: the first naturally endogenous azo compound and toxic phenolic metabolites

Z Naturforsch C Biosci. 1984 Nov-Dec;39(11-12):1027-9. doi: 10.1515/znc-1984-11-1203.

Abstract

Extraction of fresh sporophores of the fungus Agaricus xanthodermus yields 4,4'-dihydroxy-azobenzene, phenol, p-quinol, and 4,4'-dihydroxybiphenyl. This is the first report of an azo compound arising endogenously in nature, while phenol, p-quinol and 4,4'-dihydroxybiphenyl have not previously been isolated from higher fungi. Phenol is present in fruitbodies in sufficiently high concentration to account for the toxicity of A. xanthodermus.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Agaricales / analysis*
  • Azo Compounds / analysis*
  • Biphenyl Compounds / analysis
  • Chromatography / methods
  • Hydroquinones / analysis
  • Mycotoxins / analysis*
  • Phenol
  • Phenols / analysis*

Substances

  • Azo Compounds
  • Biphenyl Compounds
  • Hydroquinones
  • Mycotoxins
  • Phenols
  • Phenol
  • 4,4'-azobis(phenol)
  • 4,4'-dihydroxybiphenyl
  • hydroquinone