Genetic basis of susceptibility for development of neoplasms following treatment with N-methyl-N-nitrosourea (MNU) or x-rays in the platyfish/swordtail system

Experientia. 1978 Jun 15;34(6):780-2. doi: 10.1007/BF01947324.

Abstract

Specific genotypes of the xiphophorine fish develop neoplasms following treatment with N-methyl-N-nitrosourea or X-rays. Several of these neoplasms can be related to the presence of specific chromosomes. The implication of these findings are discussed.

MeSH terms

  • Animals
  • Chromosomes
  • Female
  • Fishes / genetics*
  • Genotype
  • Male
  • Methylnitrosourea
  • Mutation
  • Neoplasms, Experimental / chemically induced
  • Neoplasms, Experimental / genetics*
  • Neoplasms, Radiation-Induced / genetics*

Substances

  • Methylnitrosourea