Abstract
A 3-day D-penicillamine treatment of neonatal rats caused a significant decrease in heme oxygenase activity. This change was not observed in adult rats. The data indicate age-related differences in the effects of D-penicillamine.
MeSH terms
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Aging
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Animals
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Animals, Newborn
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Heme Oxygenase (Decyclizing) / metabolism*
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Liver / drug effects
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Liver / enzymology*
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Liver / growth & development
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Male
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Mixed Function Oxygenases / metabolism*
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Penicillamine / pharmacology*
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Rats
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Rats, Inbred Strains
Substances
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Mixed Function Oxygenases
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Heme Oxygenase (Decyclizing)
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Penicillamine