Abstract
A study was made of adverse dermatological reactions to the non-steroidal anti-inflammatory agent benoxaprofen. Photosensitivity was seen in several patients, confined to wavelengths less than 340 nm. Other cutaneous side effects were erythema multiforme, the Stevens-Johnson syndrome, milia, and onycholysis. One case of pancytopenia and toxic epidermal necrolysis was reported. patients were not rechallenged with the drug, but these reactions appear to be true side effects of benoxaprofen.
MeSH terms
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Aged
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Anti-Inflammatory Agents / adverse effects*
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Anti-Inflammatory Agents / therapeutic use
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Epidermal Cyst / chemically induced
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Erythema Multiforme / chemically induced
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Female
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Humans
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Middle Aged
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Nail Diseases / chemically induced
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Photosensitivity Disorders / chemically induced
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Propionates / adverse effects*
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Propionates / therapeutic use
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Prurigo / drug therapy
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Rheumatic Diseases / drug therapy
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Skin Diseases / chemically induced*
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Stevens-Johnson Syndrome / chemically induced
Substances
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Anti-Inflammatory Agents
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Propionates
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benoxaprofen