Abstract
Vitreous from patients with proliferative diabetic retinopathy contains an angiogenic substance which stimulates the proliferation of blood vessels on the chick chorioallantoic membrane, whereas vitreous from non-diabetics who do not have a proliferative retinopathy does not.
MeSH terms
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Allantois / blood supply
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Allantois / drug effects
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Angiogenesis Inducing Agents / isolation & purification*
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Angiogenesis Inducing Agents / pharmacology
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Animals
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Biological Assay
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Chick Embryo
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Chorion / blood supply
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Chorion / drug effects
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Diabetic Retinopathy / metabolism*
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Growth Substances / isolation & purification*
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Humans
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Vitreous Body / analysis*
Substances
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Angiogenesis Inducing Agents
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Growth Substances