Comparison of plasma concentrations of vitamin D and its metabolites in young and aged domestic animals

Comp Biochem Physiol B. 1982;73(3):485-9. doi: 10.1016/0305-0491(82)90064-5.

Abstract

1. Vitamin D and its metabolites were measured in the plasma of five species of rural domestic animals. 2. Concentration of 1,25-dihydroxyvitamin D was higher (P less than 0.01) in young animals (range 24-118 pg/ml, means +/- SD = 72.0 +/- 30.0) than in adult animals (range 14-67 pg/ml, means +/- SD = 40.2 +/- 22.6). 3. 25-Hydroxyvitamin D3-26,23 lactone was present only in the chick and the pig. 4. Unsheared sheep appeared to be inefficient utilizers of the photochemical conversion of 7-dehydrocholesterol to vitamin D3. 5. Conversion of 25-hydroxyvitamin D to 24,25-dihydroxyvitamin D was most efficient in species with high plasma phosphorus concentrations (pig, sheep).

Publication types

  • Comparative Study

MeSH terms

  • 24,25-Dihydroxyvitamin D 3
  • Aging*
  • Animals
  • Animals, Domestic / blood*
  • Calcifediol / analogs & derivatives
  • Calcifediol / blood
  • Calcitriol / blood
  • Cattle
  • Chickens
  • Dihydroxycholecalciferols / blood
  • Female
  • Male
  • Sheep
  • Swine
  • Turkeys
  • Vitamin D / blood*

Substances

  • Dihydroxycholecalciferols
  • Vitamin D
  • 24,25-Dihydroxyvitamin D 3
  • calcifediol lactone
  • Calcitriol
  • Calcifediol