[Use of Aloglutamol in uremic patients on dialysis (author's transl]

Urol Int. 1978;33(4):213-21. doi: 10.1159/000280201.
[Article in French]

Abstract

The authors experimented Aloglutamol (an organic salt of aluminium) in uremic patients on dialysis to detect its phosphate-binding properties and study its use in the treatment of uremic osteodystropy. They report good results: predialysis Ca increased; serum PO4 and alcaline phosphatase levels decreased; Ca X PO4 was normalized; itch, muscular weakness and constipation decreased; no side-effects appeared, and the drug has a good taste. Therefore it is considered to be most useful in the treatment of hyperphosphatemia in uremia.

MeSH terms

  • Adult
  • Aluminum / therapeutic use*
  • Calcium / blood
  • Chronic Kidney Disease-Mineral and Bone Disorder / blood
  • Chronic Kidney Disease-Mineral and Bone Disorder / drug therapy
  • Female
  • Gluconates
  • Humans
  • Male
  • Middle Aged
  • Phosphates / blood
  • Renal Dialysis*
  • Tromethamine / analogs & derivatives
  • Uremia / blood
  • Uremia / drug therapy*

Substances

  • Gluconates
  • Phosphates
  • Tromethamine
  • Aluminum
  • Calcium