Differential effects of Clostridium difficile toxins on tissue-cultured cells

J Clin Microbiol. 1982 Jun;15(6):1157-8. doi: 10.1128/jcm.15.6.1157-1158.1982.

Abstract

Two immunologically distinct Clostridium difficile toxins elicited similar morphological changes on cultured cells, although there were differences in both toxin potency and cell sensitivities.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Bacterial Toxins / pharmacology*
  • Cell Line
  • Cells, Cultured / cytology*
  • Clostridium*
  • Cricetinae
  • Cricetulus
  • Cytotoxins / pharmacology*
  • Female
  • HeLa Cells
  • Humans
  • Mice
  • Rats

Substances

  • Bacterial Toxins
  • Cytotoxins