Abstract
The analgesic effect of a single intravenous dose of dezocine at various dosage levels was studied in 41 patients suffering from acute renal colic. Twenty milligrams was found to be a very effective dose. Out of 25 injections an excellent response was recorded on 21 occasions, with a mean duration of effect of 3.5 hours. In a further 3 patients, pain relief was considered as fair and of shorter duration. Pronounced dizziness was a nearly constant side-effect of the drug. There was no overall effect on blood pressure or heart rate.
MeSH terms
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Analgesics / administration & dosage*
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Analgesics / adverse effects*
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Analgesics / therapeutic use
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Bridged Bicyclo Compounds, Heterocyclic
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Bridged-Ring Compounds / administration & dosage*
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Bridged-Ring Compounds / adverse effects
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Bridged-Ring Compounds / therapeutic use
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Colic / drug therapy*
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Cycloparaffins / administration & dosage*
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Cycloparaffins / adverse effects
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Cycloparaffins / therapeutic use
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Dizziness / chemically induced
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Humans
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Kidney Diseases / drug therapy*
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Tetrahydronaphthalenes
Substances
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Analgesics
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Bridged Bicyclo Compounds, Heterocyclic
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Bridged-Ring Compounds
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Cycloparaffins
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Tetrahydronaphthalenes
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dezocine