Preliminary clinical experience with dezocine, a new potent analgesic

Curr Med Res Opin. 1980;6(7):472-4. doi: 10.1185/03007998009109470.

Abstract

The analgesic effect of a single intravenous dose of dezocine at various dosage levels was studied in 41 patients suffering from acute renal colic. Twenty milligrams was found to be a very effective dose. Out of 25 injections an excellent response was recorded on 21 occasions, with a mean duration of effect of 3.5 hours. In a further 3 patients, pain relief was considered as fair and of shorter duration. Pronounced dizziness was a nearly constant side-effect of the drug. There was no overall effect on blood pressure or heart rate.

MeSH terms

  • Analgesics / administration & dosage*
  • Analgesics / adverse effects*
  • Analgesics / therapeutic use
  • Bridged Bicyclo Compounds, Heterocyclic
  • Bridged-Ring Compounds / administration & dosage*
  • Bridged-Ring Compounds / adverse effects
  • Bridged-Ring Compounds / therapeutic use
  • Colic / drug therapy*
  • Cycloparaffins / administration & dosage*
  • Cycloparaffins / adverse effects
  • Cycloparaffins / therapeutic use
  • Dizziness / chemically induced
  • Humans
  • Kidney Diseases / drug therapy*
  • Tetrahydronaphthalenes

Substances

  • Analgesics
  • Bridged Bicyclo Compounds, Heterocyclic
  • Bridged-Ring Compounds
  • Cycloparaffins
  • Tetrahydronaphthalenes
  • dezocine