Phenelzine reduces plasma vitamin B6

J Psychiatry Neurosci. 1994 Nov;19(5):332-4.

Abstract

Plasma levels of the active form of vitamin B6 (pyridoxal phosphate) in 19 patients taking phenelzine were found to be reduced on the average to approximately 54% of the value in a control group. There was no correlation of pyridoxal phosphate level with phenelzine daily dosage over the range of 30 mg to 90 mg. No symptoms of vitamin B6 deficiency peripheral neuropathy were found.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Depressive Disorder / diagnosis
  • Depressive Disorder / drug therapy*
  • Depressive Disorder / psychology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Panic Disorder / diagnosis
  • Panic Disorder / drug therapy*
  • Panic Disorder / psychology
  • Phenelzine / administration & dosage
  • Phenelzine / pharmacology*
  • Phenelzine / therapeutic use*
  • Plasma / drug effects*
  • Psychiatric Status Rating Scales
  • Pyridoxal Phosphate / blood*
  • Pyridoxal Phosphate / metabolism*

Substances

  • Pyridoxal Phosphate
  • Phenelzine