Mechanism of leflunomide-induced prevention of xenoantibody formation and xenograft rejection in the hamster to rat heart transplantation model

Transplant Proc. 1995 Feb;27(1):305-6.

Authors

Y Lin¹, H Sobis, M Vandeputte, M Waer

Affiliation

¹ Laboratory for Experimental Transplantation, University of Leuven, Belgium.

PMID: 7879012

No abstract available

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Antibodies, Heterophile / biosynthesis*
Antibody Formation / drug effects
Complement System Proteins / immunology
Cricetinae
Cyclosporine / therapeutic use
Cytotoxicity, Immunologic
Flow Cytometry
Graft Rejection / immunology
Graft Rejection / prevention & control*
Graft Survival / drug effects
Graft Survival / immunology*
Heart Transplantation / immunology*
Immunosuppressive Agents / pharmacology*
Isoxazoles / pharmacology*
Leflunomide
Male
Mesocricetus
Rats
Rats, Inbred Strains
Rats, Nude
Transplantation, Heterologous / immunology*

Substances

Antibodies, Heterophile
Immunosuppressive Agents
Isoxazoles
Cyclosporine
Complement System Proteins
Leflunomide