Eudistomin U and isoeudistomin U, new alkaloids from the Caribbean ascidian Lissoclinum fragile

J Nat Prod. 1994 Apr;57(4):528-33. doi: 10.1021/np50106a016.

Abstract

Chemical investigations of the Caribbean ascidian Lissoclinum fragile (Didemnidae) have resulted in the isolation of new alkaloids which we have designated eudistomin U [1] and isoeudistomin U [2]. Their structures were determined by spectrometric and chemical means.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Agrobacterium tumefaciens / drug effects
  • Alkaloids / chemistry
  • Alkaloids / isolation & purification*
  • Animals
  • Carbolines / chemical synthesis*
  • Carbolines / pharmacology
  • Drug Screening Assays, Antitumor
  • Humans
  • In Vitro Techniques
  • Magnetic Resonance Spectroscopy
  • Mass Spectrometry
  • Microbial Sensitivity Tests
  • Spectrophotometry, Infrared
  • Tumor Cells, Cultured
  • Urochordata / chemistry*

Substances

  • Alkaloids
  • Carbolines
  • eudistomin U
  • isoeudistomin U