Inflammatory pseudotumor is uncommon in the field of otorhinolaryngology. It is often misdiagnosed as a malignant tumor and undergone radical operation because of its extensive infiltration and bony destruction. Three cases of primary pseudotumor of the nose are reported in this paper. Two of them had involved the nasal cavity and sinuses, orbit and anterior cranial fossa. Reports of such extensive inflammatory pseudotumor has been few in Chinese and foreign literatures. The tumor is sensitive to cortical hormone therapy. An extensive lesion not being confirmed pathologically as a malignant neoplasm should be suspected of inflammatory pseudotumor and can be tentatively treated with cortical hormone, radical operation should be avoided until a diagnosis of malignant tumor is established.