Gamma globulin re-treatment in Kawasaki disease

R P Sundel; J C Burns; A Baker; A S Beiser; J W Newburger

doi:10.1016/s0022-3476(05)80972-2

Gamma globulin re-treatment in Kawasaki disease

J Pediatr. 1993 Oct;123(4):657-9. doi: 10.1016/s0022-3476(05)80972-2.

Authors

R P Sundel¹, J C Burns, A Baker, A S Beiser, J W Newburger

Affiliation

¹ Department of Medicine, Children's Hospital, Boston, Massachusetts 02115.

PMID: 8410524
DOI: 10.1016/s0022-3476(05)80972-2

Abstract

We retrospectively reviewed the effects of intravenous gamma-globulin (IVGG) re-treatment of 13 children with Kawasaki disease and persistent or recrudescent fever. Fever and mucocutaneous inflammation resolved within 48 hours in nine patients; fever abated in two other children after a third course of IVGG. We conclude that IVGG re-treatment of Kawasaki disease appears to be safe and may improve the clinical course.

MeSH terms

Child, Preschool
Female
Humans
Immunoglobulins, Intravenous / therapeutic use*
Male
Mucocutaneous Lymph Node Syndrome / epidemiology
Mucocutaneous Lymph Node Syndrome / therapy*
Retrospective Studies
Treatment Failure

Substances

Immunoglobulins, Intravenous