Oral candidiasis established in the sialoadenectomised rat

J Oral Pathol Med. 1993 Feb;22(2):54-6. doi: 10.1111/j.1600-0714.1993.tb00042.x.

Abstract

Xerostomia provoked in rats by surgical removal of the major salivary glands favoured the development of oral candidiasis. After 32 weeks of inoculation, 20% of normal and 70% of xerostomic rats showed candidal infection on the tongue but only in xerostomic rats did candidiasis affect the pharyngeal aspect of the tongue.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Candidiasis, Oral / etiology*
  • Candidiasis, Oral / microbiology
  • Candidiasis, Oral / pathology
  • Disease Models, Animal
  • Male
  • Rats
  • Rats, Wistar
  • Salivary Glands / physiology
  • Salivary Glands / surgery
  • Tongue Diseases / etiology
  • Tongue Diseases / microbiology
  • Tongue Diseases / pathology
  • Xerostomia / complications*