A model for the involvement of MHC class II proteins in the development of type 1 (insulin-dependent) diabetes mellitus in response to bovine serum albumin peptides

Diabetologia. 1993 Apr;36(4):364-8. doi: 10.1007/BF00400243.

Authors

B H Robinson¹, H M Dosch, J M Martin, H K Akerblom, E Savilahti, M Knip, J Ilonen

Affiliation

¹ Department of Biochemistry, Hospital for Sick Children, Toronto, Ontario, Canada.

PMID: 8477884
DOI: 10.1007/BF00400243

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Amino Acid Sequence
Animals
Cattle
Diabetes Mellitus, Type 1 / genetics
Diabetes Mellitus, Type 1 / immunology*
Diabetes Mellitus, Type 1 / prevention & control
Female
Genetic Predisposition to Disease
HLA-DQ Antigens / genetics
HLA-DQ Antigens / physiology*
HLA-DQ beta-Chains
Humans
Insulin / metabolism
Insulin Secretion
Islets of Langerhans / immunology
Islets of Langerhans / metabolism
Milk / immunology*
Models, Biological
Molecular Sequence Data
Rats
Rats, Inbred BB
Serum Albumin, Bovine / immunology*

Substances

HLA-DQ Antigens
HLA-DQ beta-Chains
HLA-DQbeta antigen
Insulin
Serum Albumin, Bovine