Abstract
Because high-dose oral dexamethasone therapy has been reported to be effective for adults with idiopathic thrombocytopenic purpura, we assessed the short-term efficacy and toxicity of dexamethasone in seven children with chronic or refractory idiopathic thrombocytopenic purpura. Dexamethasone therapy was effective and well tolerated; further long-term studies are warranted.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adolescent
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Anti-Inflammatory Agents / administration & dosage
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Anti-Inflammatory Agents / therapeutic use*
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Child
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Child, Preschool
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Dexamethasone / administration & dosage
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Dexamethasone / adverse effects
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Dexamethasone / therapeutic use*
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Dose-Response Relationship, Drug
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Female
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Humans
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Male
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Platelet Count
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Purpura, Thrombocytopenic / drug therapy*
Substances
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Anti-Inflammatory Agents
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Dexamethasone