Abstract
The addition of 0.5% of ascorbic acid to the lithogenic diet of golden hamsters whose body pool was labelled with 26-14C-cholesterol, lowered the formation of gallstones, the cholesterol concentration and half-life in blood plasma and in the liver, and accelerated cholesterol transformation to bile acids.
MeSH terms
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Animals
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Ascorbic Acid / therapeutic use*
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Ascorbic Acid Deficiency / complications
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Bile Acids and Salts / biosynthesis
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Cholelithiasis / etiology
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Cholelithiasis / prevention & control*
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Cholesterol / blood
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Cholesterol / metabolism
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Cricetinae
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Liver / metabolism
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Male
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Mesocricetus
Substances
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Bile Acids and Salts
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Cholesterol
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Ascorbic Acid