Abstract
Sequences for two reovirus ribosome-protected fragments are presented. Comparison with four other reovirus initiation sites reveals only two common features: the 5'-terminal sequence m7GpppGmCUA, and (located 15-33 nucleotides from the cap) the sequence AUGG. Both the cap and the AUG codon are included in the 40S-ribosome protected region from all six reovirus messages.
MeSH terms
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Base Sequence
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Binding Sites
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Codon
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Guanosine Pentaphosphate / metabolism
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Peptide Chain Initiation, Translational*
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RNA, Messenger* / isolation & purification
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RNA, Messenger* / metabolism
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RNA, Viral* / isolation & purification
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RNA, Viral* / metabolism
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Reoviridae / metabolism*
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Ribosomes / metabolism*
Substances
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Codon
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RNA, Messenger
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RNA, Viral
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Guanosine Pentaphosphate