Bilateral Candida parapsilosis endophthalmitis

Arch Ophthalmol. 1997 May;115(5):670-2. doi: 10.1001/archopht.1997.01100150672022.

Abstract

We describe a patient with bilateral, delayed endophthalmitis who underwent bilateral pars plana vitrectomy, total capsulectomy, intraocular lens exchange, intravitreal injection of amphotericin B, and oral fluconazole therapy. The long-term inflammation resolved, and vitreous cultures from both eyes yielded Candida parapsilosis. Histopathologic examination revealed sequestered yeast forms in the capsular bags.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Amphotericin B / therapeutic use
  • Antifungal Agents / therapeutic use
  • Candida / isolation & purification*
  • Candidiasis / drug therapy
  • Candidiasis / etiology*
  • Endophthalmitis / drug therapy
  • Endophthalmitis / microbiology*
  • Eye Infections, Fungal / drug therapy
  • Eye Infections, Fungal / etiology*
  • Fluconazole / therapeutic use
  • Humans
  • Injections
  • Lens Capsule, Crystalline / microbiology
  • Lenses, Intraocular
  • Male
  • Phacoemulsification / adverse effects*
  • Visual Acuity
  • Vitrectomy

Substances

  • Antifungal Agents
  • Amphotericin B
  • Fluconazole