FISH localization of the human Y-homolog of protein kinase PRKX (PRKY) to Yp11.2 and two pseudogenes to 15q26 and Xq12-->q13

K Schiebel; A Mertz; M Winkelmann; B Gläser; W Schempp; G Rappold

doi:10.1159/000134514

FISH localization of the human Y-homolog of protein kinase PRKX (PRKY) to Yp11.2 and two pseudogenes to 15q26 and Xq12-->q13

Cytogenet Cell Genet. 1997;76(1-2):49-52. doi: 10.1159/000134514.

Authors

K Schiebel¹, A Mertz, M Winkelmann, B Gläser, W Schempp, G Rappold

Affiliation

¹ Institute of Human Genetics, University of Heidelberg, Germany.

PMID: 9154127
DOI: 10.1159/000134514

Abstract

Recently, we reported the isolation of a new subfamily of serine-threonine protein kinases. This subfamily was shown to consist of at least four members. Sequencing and FISH mapping of all 4 members now reveals that the Y-homolog (PRKY) of the previously mapped PRKX gene (Xp22.3) is located in Yp11.2, in close vicinity to AMELY. The other two copies reside on Xq12-->q13 (PRKXP2) and 15q26 (PRKXP1, containing CA repeat STS D15S87) and represent pseudogenes.

Publication types

Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Base Sequence
Chromosome Mapping
Chromosomes, Human, Pair 15*
DNA, Complementary
Female
Humans
In Situ Hybridization, Fluorescence
Male
Molecular Sequence Data
Protein Serine-Threonine Kinases / genetics*
Pseudogenes*
X Chromosome*
Y Chromosome*

Substances

DNA, Complementary
Protein Serine-Threonine Kinases

Associated data

GENBANK/X85545
GENBANK/Y10481
GENBANK/Y10482
GENBANK/Y10483
GENBANK/Y10484
GENBANK/Y10485