Aspirin use and potential mechanisms for colorectal cancer prevention

J Clin Invest. 1997 Sep 15;100(6):1325-9. doi: 10.1172/JCI119651.
No abstract available

Publication types

  • Review

MeSH terms

  • Adenocarcinoma / chemistry
  • Adenomatous Polyps / chemistry
  • Adenomatous Polyps / physiopathology
  • Adenomatous Polyps / prevention & control*
  • Animals
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Aspirin / pharmacology
  • Aspirin / therapeutic use*
  • Colorectal Neoplasms / chemistry
  • Colorectal Neoplasms / physiopathology
  • Colorectal Neoplasms / prevention & control*
  • Cyclooxygenase 2
  • Cyclooxygenase 2 Inhibitors
  • Cyclooxygenase Inhibitors / pharmacology
  • Gene Expression Regulation, Neoplastic
  • Humans
  • Isoenzymes / analysis
  • Isoenzymes / physiology*
  • Male
  • Membrane Proteins
  • Mice
  • Prostaglandin-Endoperoxide Synthases / analysis
  • Prostaglandin-Endoperoxide Synthases / physiology*
  • Randomized Controlled Trials as Topic
  • Sulindac / pharmacology
  • Sulindac / therapeutic use

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Cyclooxygenase 2 Inhibitors
  • Cyclooxygenase Inhibitors
  • Isoenzymes
  • Membrane Proteins
  • Sulindac
  • Cyclooxygenase 2
  • PTGS2 protein, human
  • Prostaglandin-Endoperoxide Synthases
  • Aspirin