Abstract
Spermadhesins, 12,000-14,000 M(r) mammalian proteins, include lectins involved in sperm-egg binding and display a single CUB domain architecture. We report the crystal structures of porcine seminal plasma PSP-I/PSP-II, a heterodimer of two glycosylated spermadhesins, and bovine aSFP at 2.4 A and 1.9 A resolution respectively.
Publication types
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Letter
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Animals
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Cattle
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Crystallography, X-Ray
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Dimerization
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Female
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Glycoproteins / chemistry*
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Glycosylation
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Macromolecular Substances
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Male
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Mammals
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Models, Structural
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Molecular Sequence Data
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Protein Conformation*
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Protein Folding*
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Semen / chemistry
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Seminal Vesicle Secretory Proteins*
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Sequence Alignment
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Sperm-Ovum Interactions
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Swine
Substances
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Glycoproteins
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Macromolecular Substances
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Seminal Vesicle Secretory Proteins
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seminal vesicle secretory protein II, porcine
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seminal vesicle secretory protein 109, porcine