Asymmetic division: dynastic intricacies of neuroblast division

Curr Biol. 1997 Nov 1;7(11):R726-8. doi: 10.1016/s0960-9822(06)00367-8.

Abstract

The cytoplasmic determinants Numb and Prospero are distributed asymmetrically into the daughter cells of Drosophila neuroblasts. The proteins encoded by the genes inscuteable, staufen and miranda are involved in the localisation of Prospero.

Publication types

  • Review

MeSH terms

  • Animals
  • Cell Division / genetics
  • Drosophila / embryology*
  • Drosophila Proteins*
  • Juvenile Hormones / genetics
  • Nerve Tissue Proteins / genetics
  • Neurons / cytology*
  • Neurons / physiology*
  • Nuclear Proteins / genetics
  • Transcription Factors*

Substances

  • Drosophila Proteins
  • Juvenile Hormones
  • Nerve Tissue Proteins
  • Nuclear Proteins
  • Transcription Factors
  • numb protein, Drosophila
  • pros protein, Drosophila