Transgenic pigs and virus adaptation

Nature. 1998 Jan 22;391(6665):327-8. doi: 10.1038/34772.

Abstract

Pigs offer the best hope of providing organs for transplantation to humans. But, in overcoming the problems of tissue rejection, we may be increasing our risk of injection from pig viruses.

MeSH terms

  • Adaptation, Physiological*
  • Animals
  • Animals, Genetically Modified / virology*
  • Graft Rejection* / immunology
  • Humans
  • Organ Transplantation
  • Receptors, Immunologic / physiology
  • Receptors, Virus / physiology
  • Risk Assessment
  • Social Control, Formal
  • Species Specificity
  • Swine / virology*
  • Transplantation, Heterologous* / adverse effects
  • Virus Physiological Phenomena*
  • Viruses / immunology

Substances

  • Receptors, Immunologic
  • Receptors, Virus