Cationic peptides: a new source of antibiotics

Trends Biotechnol. 1998 Feb;16(2):82-8. doi: 10.1016/s0167-7799(97)01156-6.

Abstract

Antimicrobial cationic peptides are an important component of the innate defenses of all species of life. Different peptides may have antibacterial, antiendotoxic, antibiotic-potentiating or antifungal properties, and so they are being developed for use as a novel class of antimicrobial agents and as the basis for making transgenic disease-resistant plants and animals.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Anti-Bacterial Agents / pharmacology*
  • Anti-Infective Agents / pharmacology*
  • Antimicrobial Cationic Peptides*
  • Blood Proteins / chemistry
  • Blood Proteins / pharmacology*
  • Cost-Benefit Analysis
  • DNA-Binding Proteins / chemistry
  • DNA-Binding Proteins / pharmacology*
  • Defensins
  • Humans
  • Infections / immunology
  • Molecular Sequence Data
  • Peptides, Cyclic / chemistry
  • Peptides, Cyclic / pharmacology*
  • Protein Structure, Secondary
  • Proteins / chemistry
  • Proteins / pharmacology*
  • Transgenes

Substances

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Antimicrobial Cationic Peptides
  • Blood Proteins
  • DNA-Binding Proteins
  • Defensins
  • Peptides, Cyclic
  • Proteins
  • protegrin-1
  • tachyplesin peptide, Tachypleus tridentatus