Aldose reductase in glucose toxicity: a potential target for the prevention of diabetic complications

Pharmacol Rev. 1998 Mar;50(1):21-33.

Author

C Yabe-Nishimura¹

Affiliation

¹ Department of Pharmacology, Kyoto Prefectural University of Medicine, Japan.

PMID: 9549756

No abstract available

Publication types

Review

MeSH terms

Alcohol Oxidoreductases / metabolism*
Aldehyde Reductase / antagonists & inhibitors
Aldehyde Reductase / chemistry
Aldehyde Reductase / metabolism
Aldehyde Reductase / physiology*
Aldo-Keto Reductases
Diabetes Complications*
Diabetes Mellitus / drug therapy
Diabetes Mellitus / enzymology
Enzyme Inhibitors / therapeutic use
Humans
Hyperglycemia / complications*
Hyperglycemia / metabolism
Hyperglycemia / therapy
Kidney / drug effects
Kidney / physiology
Male
Protein Structure, Tertiary
Seminal Vesicles / drug effects
Seminal Vesicles / physiology
Substrate Specificity

Substances

Enzyme Inhibitors
Alcohol Oxidoreductases
Aldo-Keto Reductases
Aldehyde Reductase