Advances in melanoma therapy

J Am Acad Dermatol. 1998 May;38(5 Pt 1):731-41. doi: 10.1016/s0190-9622(98)70202-6.

Abstract

This review discusses several advances in melanoma therapy that have recently occurred or are presently in a developmental stage. We discuss the history and present dogma regarding assessment of the regional lymph nodes and adjuvant therapy for melanoma. Of special interest is radiolymphatic sentinel node mapping of the lymph nodes and adjuvant interferon alfa-2b for thick primary lesions and stage III disease. We also discuss several evolving novel and innovative genetic immunotherapy approaches for patients with stage IV disease.

Publication types

  • Review

MeSH terms

  • Chemotherapy, Adjuvant
  • Genetic Techniques
  • Humans
  • Immunotherapy
  • Interferon alpha-2
  • Interferon-alpha / therapeutic use
  • Lymph Nodes / diagnostic imaging
  • Lymph Nodes / pathology
  • Lymphatic Metastasis
  • Melanoma / diagnostic imaging
  • Melanoma / pathology
  • Melanoma / secondary
  • Melanoma / therapy*
  • Neoplasm Staging
  • Radiology, Interventional
  • Radionuclide Imaging
  • Radiopharmaceuticals
  • Radiotherapy, Adjuvant
  • Recombinant Proteins
  • Rosaniline Dyes
  • Skin Neoplasms / pathology
  • Skin Neoplasms / therapy*

Substances

  • Interferon alpha-2
  • Interferon-alpha
  • Radiopharmaceuticals
  • Recombinant Proteins
  • Rosaniline Dyes
  • iso-sulfan blue