Pain on injection of propofol

Anaesthesia. 1998 May;53(5):468-76. doi: 10.1046/j.1365-2044.1998.00405.x.

Abstract

Pain on injection of propofol is a common problem, the cause of which remains unknown. The chemical properties and preparation of propofol, proposed mechanisms for the cause of the pain and clinical strategies to prevent pain on injection of propofol are reviewed in the hope of shedding some light on the subject.

Publication types

  • Review

MeSH terms

  • Anesthetics, Intravenous / adverse effects*
  • Anesthetics, Intravenous / chemistry
  • Anesthetics, Local / therapeutic use
  • Chemistry, Pharmaceutical
  • Humans
  • Injections, Intravenous / adverse effects
  • Lidocaine / therapeutic use
  • Pain / chemically induced*
  • Pain / prevention & control
  • Propofol / adverse effects*
  • Propofol / chemistry

Substances

  • Anesthetics, Intravenous
  • Anesthetics, Local
  • Lidocaine
  • Propofol