Biotransformation of resveratrol to piceid by Bacillus cereus

J Nat Prod. 1998 Oct;61(10):1313-4. doi: 10.1021/np980139b.

Abstract

Microbial transformation of resveratrol (1), trans-3,4', 5-trihydroxystilbene, was studied. Preparative scale biotransformation of 1 with whole-cell suspensions of Bacillus cereus UI 1477 resulted in the production of metabolite 2 which was identical in all respects to an authentic sample of piceid, resveratrol 3-O-beta-D-glucoside.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Antineoplastic Agents, Phytogenic / metabolism
  • Antioxidants / metabolism
  • Bacillus cereus / metabolism*
  • Biotransformation
  • Enzyme Inhibitors / metabolism
  • Glucosides / chemistry
  • Glucosides / metabolism*
  • Models, Biological
  • Molecular Structure
  • Platelet Aggregation Inhibitors / metabolism
  • Resveratrol
  • Stilbenes / chemistry
  • Stilbenes / metabolism*

Substances

  • Antineoplastic Agents, Phytogenic
  • Antioxidants
  • Enzyme Inhibitors
  • Glucosides
  • Platelet Aggregation Inhibitors
  • Stilbenes
  • Resveratrol
  • polydatin