Cellular magnesium transport in the vertebrate intestine

Magnes Res. 1998 Dec;11(4):315-22.

Abstract

Magnesium (Mg) absorption across the intestinal epithelium is crucial for Mg homeostasis in all vertebrates. Besides paracellular transport, it involves a cell-mediated component, and this predicts the presence of specific Mg carriers at both the apical and basolateral pole of the epithelial cells. Although the mechanism of transmembrane Mg transport in enterocytes, as in most cell types, has remained an elusive topic for many years, recent studies have provided promising new insights. We here recapitulate the progress that has been made in this field, and advance evidence for membrane carriers that are involved in transcellular Mg transport in the intestine.

Publication types

  • Review

MeSH terms

  • Animals
  • Biological Transport
  • Cell Membrane / metabolism
  • Humans
  • Intestinal Absorption / physiology
  • Intestinal Mucosa / metabolism*
  • Intestines / cytology
  • Magnesium / metabolism*
  • Vertebrates / physiology*

Substances

  • Magnesium