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Page 1
The oxido-reductase activity of the apoptosis inducing factor: a promising pharmacological tool?
Curr Pharm Des. 2013;19(14):2628-36. doi: 10.2174/1381612811319140012.
Curr Pharm Des. 2013.
PMID: 23116400
Review.
Beyond a platform protein for the degradosome assembly: The Apoptosis-Inducing Factor as an efficient nuclease involved in chromatinolysis.
Novo N, Romero-Tamayo S, Marcuello C, Boneta S, Blasco-Machin I, Velázquez-Campoy A, Villanueva R, Moreno-Loshuertos R, Lostao A, Medina M, Ferreira P.
Novo N, et al. Among authors: villanueva r.
PNAS Nexus. 2022 Dec 26;2(2):pgac312. doi: 10.1093/pnasnexus/pgac312. eCollection 2023 Feb.
PNAS Nexus. 2022.
PMID: 36845352
Free PMC article.
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Structural insights into the coenzyme mediated monomer-dimer transition of the pro-apoptotic apoptosis inducing factor.
Ferreira P, Villanueva R, Martínez-Júlvez M, Herguedas B, Marcuello C, Fernandez-Silva P, Cabon L, Hermoso JA, Lostao A, Susin SA, Medina M.
Ferreira P, et al. Among authors: villanueva r.
Biochemistry. 2014 Jul 1;53(25):4204-15. doi: 10.1021/bi500343r. Epub 2014 Jun 20.
Biochemistry. 2014.
PMID: 24914854
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Structural insights into the mechanism of protein O-fucosylation.
Lira-Navarrete E, Valero-González J, Villanueva R, Martínez-Júlvez M, Tejero T, Merino P, Panjikar S, Hurtado-Guerrero R.
Lira-Navarrete E, et al. Among authors: villanueva r.
PLoS One. 2011;6(9):e25365. doi: 10.1371/journal.pone.0025365. Epub 2011 Sep 26.
PLoS One. 2011.
PMID: 21966509
Free PMC article.
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W196 and the β-Hairpin Motif Modulate the Redox Switch of Conformation and the Biomolecular Interaction Network of the Apoptosis-Inducing Factor.
Romero-Tamayo S, Laplaza R, Velazquez-Campoy A, Villanueva R, Medina M, Ferreira P.
Romero-Tamayo S, et al. Among authors: villanueva r.
Oxid Med Cell Longev. 2021 Jan 15;2021:6673661. doi: 10.1155/2021/6673661. eCollection 2021.
Oxid Med Cell Longev. 2021.
PMID: 33510840
Free PMC article.
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Redox- and Ligand Binding-Dependent Conformational Ensembles in the Human Apoptosis-Inducing Factor Regulate Its Pro-Life and Cell Death Functions.
Villanueva R, Romero-Tamayo S, Laplaza R, Martínez-Olivan J, Velázquez-Campoy A, Sancho J, Ferreira P, Medina M.
Villanueva R, et al.
Antioxid Redox Signal. 2019 Jun 20;30(18):2013-2029. doi: 10.1089/ars.2018.7658. Epub 2019 Jan 11.
Antioxid Redox Signal. 2019.
PMID: 30450916
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Key Residues Regulating the Reductase Activity of the Human Mitochondrial Apoptosis Inducing Factor.
Villanueva R, Ferreira P, Marcuello C, Usón A, Miramar MD, Peleato ML, Lostao A, Susin SA, Medina M.
Villanueva R, et al.
Biochemistry. 2015 Aug 25;54(33):5175-84. doi: 10.1021/acs.biochem.5b00696. Epub 2015 Aug 13.
Biochemistry. 2015.
PMID: 26237213
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