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Obtusaquinone: A Cysteine-Modifying Compound That Targets Keap1 for Degradation.
Badr CE, da Hora CC, Kirov AB, Tabet E, Amante R, Maksoud S, Nibbs AE, Fitzsimons E, Boukhali M, Chen JW, Chiu NHL, Nakano I, Haas W, Mazitschek R, Tannous BA. Badr CE, et al. Among authors: kirov ab. ACS Chem Biol. 2020 Jun 19;15(6):1445-1454. doi: 10.1021/acschembio.0c00104. Epub 2020 May 8. ACS Chem Biol. 2020. PMID: 32338864 Free PMC article.
BCL-XL is crucial for progression through the adenoma-to-carcinoma sequence of colorectal cancer.
Ramesh P, Lannagan TRM, Jackstadt R, Atencia Taboada L, Lansu N, Wirapati P, van Hooff SR, Dekker D, Pritchard J, Kirov AB, van Neerven SM, Tejpar S, Kops GJPL, Sansom OJ, Medema JP. Ramesh P, et al. Among authors: kirov ab. Cell Death Differ. 2021 Dec;28(12):3282-3296. doi: 10.1038/s41418-021-00816-w. Epub 2021 Jun 11. Cell Death Differ. 2021. PMID: 34117376 Free PMC article.
Stearoyl CoA Desaturase Is Essential for Regulation of Endoplasmic Reticulum Homeostasis and Tumor Growth in Glioblastoma Cancer Stem Cells.
Pinkham K, Park DJ, Hashemiaghdam A, Kirov AB, Adam I, Rosiak K, da Hora CC, Teng J, Cheah PS, Carvalho L, Ganguli-Indra G, Kelly A, Indra AK, Badr CE. Pinkham K, et al. Among authors: kirov ab. Stem Cell Reports. 2019 Apr 9;12(4):712-727. doi: 10.1016/j.stemcr.2019.02.012. Epub 2019 Mar 28. Stem Cell Reports. 2019. PMID: 30930246 Free PMC article.