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Page 1
The integrated stress response is tumorigenic and constitutes a therapeutic liability in KRAS-driven lung cancer.
Nat Commun. 2021 Jul 30;12(1):4651. doi: 10.1038/s41467-021-24661-0.
Nat Commun. 2021.
PMID: 34330898
Free PMC article.
An integrated stress response via PKR suppresses HER2+ cancers and improves trastuzumab therapy.
Darini C, Ghaddar N, Chabot C, Assaker G, Sabri S, Wang S, Krishnamoorthy J, Buchanan M, Aguilar-Mahecha A, Abdulkarim B, Deschenes J, Torres J, Ursini-Siegel J, Basik M, Koromilas AE.
Darini C, et al.
Nat Commun. 2019 May 13;10(1):2139. doi: 10.1038/s41467-019-10138-8.
Nat Commun. 2019.
PMID: 31086176
Free PMC article.
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Lopinavir co-induces insulin resistance and ER stress in human adipocytes.
Djedaini M, Peraldi P, Drici MD, Darini C, Saint-Marc P, Dani C, Ladoux A.
Djedaini M, et al. Among authors: darini c.
Biochem Biophys Res Commun. 2009 Aug 14;386(1):96-100. doi: 10.1016/j.bbrc.2009.05.148. Epub 2009 Jun 6.
Biochem Biophys Res Commun. 2009.
PMID: 19501568
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STAT1 Promotes KRAS Colon Tumor Growth and Susceptibility to Pharmacological Inhibition of Translation Initiation Factor eIF4A.
Wang S, Darini C, Désaubry L, Koromilas AE.
Wang S, et al. Among authors: darini c.
Mol Cancer Ther. 2016 Dec;15(12):3055-3063. doi: 10.1158/1535-7163.MCT-16-0416.
Mol Cancer Ther. 2016.
PMID: 27913706
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Downregulation of PERK activity and eIF2α serine 51 phosphorylation by mTOR complex 1 elicits pro-oxidant and pro-death effects in tuberous sclerosis-deficient cells.
Krishnamoorthy J, Tenkerian C, Gupta J, Ghaddar N, Wang S, Darini C, Staschke KA, Ghosh A, Gandin V, Topisirovic I, Kristof AS, Hatzoglou M, Simos G, Koromilas AE.
Krishnamoorthy J, et al. Among authors: darini c.
Cell Death Dis. 2018 Feb 15;9(3):254. doi: 10.1038/s41419-018-0326-2.
Cell Death Dis. 2018.
PMID: 29449538
Free PMC article.
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Breast cancer mammospheres secrete Adrenomedullin to induce lipolysis and browning of adjacent adipocytes.
Paré M, Darini CY, Yao X, Chignon-Sicard B, Rekima S, Lachambre S, Virolle V, Aguilar-Mahecha A, Basik M, Dani C, Ladoux A.
Paré M, et al. Among authors: darini cy.
BMC Cancer. 2020 Aug 20;20(1):784. doi: 10.1186/s12885-020-07273-7.
BMC Cancer. 2020.
PMID: 32819314
Free PMC article.
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Methods to study primary tumor cells and residual tumor cells in mouse models of oncogene dependence.
Botta C, Darini C, Darrasse-Jèze G, Podsypanina K.
Botta C, et al. Among authors: darini c.
Methods Mol Biol. 2015;1267:381-94. doi: 10.1007/978-1-4939-2297-0_19.
Methods Mol Biol. 2015.
PMID: 25636480
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